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师资队伍

张振伟

张振伟,男,博士,教授,硕士研究生导师。入“广西高等学校千名中青年骨干教师培育计划(第三期)”,香港中文大学化学系访问学者,中国科学院广州生物医药与健康研究院博士后,中国民族医药学会健康产业分会常务理事,中国民族医药学会壮医药分会理事中国化学会会员。主持完成广西自然科学基金等科研项目3项、校级多项参与完成国家自然科学基金等各级科研课题多项;申报国家发明专利多项,已授权1项。以独立/共同通讯作者或第一作者在J. Am. Chem. Soc.J. Org. Chem.SynthesisRSC Med. Chem.RSC Adv.等国内外学术期刊发表论文20余篇,其中SCI收录10篇。主讲本科生及硕士研究生的《药物化学专论》、《药物化学》、《药学专业英语》《药物合成反应》及《制药工艺学》等课程的教学工作。主持完成自治区级教改项目1项,参与自治区级教改课题多项,校级教学成果一等奖1二等奖1。指导硕士研究生/本科生完成国家级和自治区级等科研创新项目10项。

招生专业:药物化学、中药学

研究方向:药物分子的设计合成与活性评价研究;新型有机小分子催化剂的设计合成与应用研究;中药化学成分及其结构修饰、活性评价研究。

联系方式:charliezh@163.com

欢迎各位同学报考beat365药物化学和中药化学专业硕士研究生!

教研室人员信息表

近年发表的学术论文

(1) Zhen-Wei Zhang, Ruo-Chen Huang (#), Yu-Hang Xie (#), Li-Zhen Li and Yan-Qiu Deng*. Biological activity-informed synthesis of quinoline-derived chiral γ-nitroketones via a bifunctional squaramide. Heterocycl. Commun., 2026, 32, 20250185.

(2) Zhen-Wei Zhang, Kai Xiong (#), Shao-Wu Liu (#), and Yan-Qiu Deng*. Dehydroabietyl squaramide incorporating chiral pyrrolidine for highly diastereo- and enantioselective Michael reaction between cyclohexanone and β-nitrostyrenes. RSC Adv., 2025, 15, 36485–36489.

(3) Zhen-Wei Zhang*, Ruo-Chen Huang (#), Kai Xiong (#), and Yan-Qiu Deng. Discovery of novel dehydroabietylamine–pyrimidine hybrids: design, synthesis and anti-tumor evaluation. RSC Med. Chem., 2025, 16, 4480–4491.

(4) Jin-Zhi He (#), Bao-Lei Zhu (#), Zhen-Hui Huang, Jin-Ping Liang, Zhen-Wei Zhang*, Qing Chen*, and Ning Lin*. Asymmetric cycloaddition of N-2,2,2-trifluoroethylisatin ketimines and unsymmetrical dicarbonyl-activated alkenes: Construction of 5′-trifluoromethylated 3,2′-pyrrolidinyl spirooxindoles with three carbonyl groups. J. Org. Chem., 2024, 89, 12924–12934.

(5) Hong-Ping Huang (#), Yu-Hang Xie (#), Xu-Mei Gan, Xin-Yu Wen, Cui-Xia Wang, Yan-Qiu Deng*, and Zhen-Wei Zhang*. Squaramide-catalyzed enantioselective Michael addition of nitromethane to 2-enoylazaarenes: synthesis of chiral azaarene-containing gnitroketones. RSC Adv., 2024, 14, 20056–20060.

(6) Feng-Ji Zhou (#), Bao-Lei Zhu (#), Zhen-Hui Huang, Ning Lin*, and Zhen-Wei Zhang*. DBU-catalyzed diastereoselective 1,3-dipolar [3+2] cycloaddition of trifluoroethyl amine-derived isatinketimines with chalcones: synthesis of 5′-CF3-substituted 3,2′-pyrrolidinyl spirooxindoles. RSC Adv., 2024, 14, 548–551.

(7) Zhen-Wei Zhang*, Shao-Wu Liu (#), Hong-Ping Huang (#), Yu-Hang Xie, Ruo-Chen Huang, Yan-Qiu Deng*, and Ning Lin*. Dehydroabietane-type bifunctional organocatalysts in asymmetric synthesis: recent progress. RSC Adv., 2023, 13, 31047–31058.

(8) Kin Boon Gan, Rong-Lin Zhong*, Zhen-Wei Zhang*, and Fuk Yee Kwong*. Atropisomeric phosphine ligands bearing C−N axial chirality: Applications in enantioselective Suzuki−Miyaura cross-coupling towards the assembly of tetra-ortho-substituted biaryls. J. Am. Chem. Soc., 2022, 144, 14864–14873. (被列为JACS同期亮点文章)

(9) Ning Lin*, Qiu-Xiang Wei, Li-Hua Jiang, Yan-Qiu Deng, Zhen-Wei Zhang*Qing Chen. Asymmetric Michael addition of malononitrile with chalcones via rosin-derived bifunctional squaramide. Catalysts, 2020, 10, 14.

(10) Wen-Run Zhu (#), Zhen-Wei Zhang (#), Wei-Hua Huang, Ning Lin*, Qing Chen*, Kai-Bin Chen, Bi-Chuan Wang, Jiang Weng, Gui Lu*. Asymmetric synthesis of vicinally bis(trifluoromethyl)-substituted 3,3’-pyrrolidinyl spirooxindoles via organocatalytic 1,3-dipolar cycloaddition reactions. Synthesis, 2019, 51, 19691979.

(11) Xin Zhao (#*), Zhen-Wei Zhang (#), Wei Cui, Shengwei Chen, Yang Zhou, Jianghong Dong, Yanling Jie, Junting Wan, Yong Xu*, Wenhui Hu*. Identification of camphor derivatives as novel M2 ion channel inhibitors of influenza A virus. Med. Chem. Comm., 2015, 6, 727731. (该期刊现已更名为:RSC Med. Chem.)